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Significados de proteasome inhibitor em inglês

russo
ингибиторы протеасомы
espanhol
inhibidores del proteasoma

Drug that blocks the action of proteasomes, cellular complexes that break down proteins.

        Termos relacionados
        ингибиторы протеасомы
        Sinônimos
        Examples for "proteasome endopeptidase complex inhibitors"
        Examples for "proteasome endopeptidase complex inhibitors"
        1
        That system is a target for anticancer strategies by using proteasome inhibitors.
        Pubmed
        2
        Nevertheless, the mechanisms of apoptosis induced by proteasome inhibitors remain unclear.
        Pubmed
        3
        Both Kyprolis and Velcade are members of a class known as proteasome inhibitors.
        Reuters
        4
        Overall, these findings suggest proteasome inhibitors as potential latency reversing agents.
        Pubmed
        5
        Overall, we determined the unique and novel mechanism of FOXM1 suppression by proteasome inhibitors.
        Pubmed
        Uso de proteasome inhibitor em inglês
        1
        The proteasome inhibitor bortezomib is an efficacious apoptotic agent in many tumor cells.
        Pubmed
        2
        Bortezomib is the first proteasome inhibitor drug tested in human patients.
        Pubmed
        3
        However, a significant proportion of patients who receive a proteasome inhibitor-containing regime show cardiotoxicity.
        Pubmed
        4
        Therefore, the proteasome inhibitor MG132 should be further evaluated for combination therapy with TRAIL.
        Pubmed
        5
        The introduction of proteasome inhibitor and immunomodulatory drugs has considerably changed the treatment paradigm of multiple myeloma.
        Pubmed
        6
        These results demonstrate the involvement of PRDM1beta in T-cell lymphoma, with possible therapeutic interference by the proteasome inhibitor.
        Pubmed
        7
        In the present study, we studied the effect of the proteasome inhibitor MLN-273 in two HBV mouse models.
        Pubmed
        8
        Finally, treatment of tumor cells with Ad-mda7 plus the proteasome inhibitor bortezomib resulted in increased tumor cell killing.
        Pubmed
        9
        Strikingly, inclusion of the proteasome inhibitor bortezomib reduces thrombotic risk, yet the molecular basis for this observation remains unknown.
        Pubmed
        10
        Rapid development of the small molecule proteasome inhibitor bortezomib has yielded important clinical benefit for patients with multiple myeloma.
        Pubmed
        11
        The proteasome inhibitor bortezomib is approved by the US Food and Drug Administration for treatment of mantle cell lymphoma.
        Pubmed
        12
        Application of the proteasome inhibitor MG132 restored the ability of the Xcv ΔxopJ to attenuate the development of leaf necrosis.
        Pubmed
        13
        We first generated a yeast strain with an epitope tagged proteasome subunit to which a proteasome inhibitor could be applied.
        Pubmed
        14
        The impact of in vitro exposure to the proteasome inhibitor bortezomib was next evaluated in primary mantle cell lymphoma cells.
        Pubmed
        15
        These studies explain a fundamental mechanism by which cells adapt to proteotoxic stress and suggest strategies to mitigate proteasome inhibitor resistance.
        Pubmed
        16
        We found that the reduction in tyrosinase levels that was induced by terrein was clearly recovered by MG-132, a proteasome inhibitor.
        Pubmed
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        Translations for proteasome inhibitor
        Proteasome inhibitor ao longo do tempo
        Proteasome inhibitor nas variantes da língua
        Estados Unidos da América
        Comum