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Significados de proteasome inhibitor em inglês

russo
ингибиторы протеасомы
espanhol
inhibidores del proteasoma

Drug that blocks the action of proteasomes, cellular complexes that break down proteins.

Termos relacionados
ингибиторы протеасомы
Sinônimos
Examples for "proteasome endopeptidase complex inhibitors"
Examples for "proteasome endopeptidase complex inhibitors"
1
That system is a target for anticancer strategies by using proteasome inhibitors.
Pubmed
2
Nevertheless, the mechanisms of apoptosis induced by proteasome inhibitors remain unclear.
Pubmed
3
Both Kyprolis and Velcade are members of a class known as proteasome inhibitors.
Reuters
4
Overall, these findings suggest proteasome inhibitors as potential latency reversing agents.
Pubmed
5
Overall, we determined the unique and novel mechanism of FOXM1 suppression by proteasome inhibitors.
Pubmed
Uso de proteasome inhibitor em inglês
1
The proteasome inhibitor bortezomib is an efficacious apoptotic agent in many tumor cells.
Pubmed
2
Bortezomib is the first proteasome inhibitor drug tested in human patients.
Pubmed
3
However, a significant proportion of patients who receive a proteasome inhibitor-containing regime show cardiotoxicity.
Pubmed
4
Therefore, the proteasome inhibitor MG132 should be further evaluated for combination therapy with TRAIL.
Pubmed
5
The introduction of proteasome inhibitor and immunomodulatory drugs has considerably changed the treatment paradigm of multiple myeloma.
Pubmed
6
These results demonstrate the involvement of PRDM1beta in T-cell lymphoma, with possible therapeutic interference by the proteasome inhibitor.
Pubmed
7
In the present study, we studied the effect of the proteasome inhibitor MLN-273 in two HBV mouse models.
Pubmed
8
Finally, treatment of tumor cells with Ad-mda7 plus the proteasome inhibitor bortezomib resulted in increased tumor cell killing.
Pubmed
9
Strikingly, inclusion of the proteasome inhibitor bortezomib reduces thrombotic risk, yet the molecular basis for this observation remains unknown.
Pubmed
10
Rapid development of the small molecule proteasome inhibitor bortezomib has yielded important clinical benefit for patients with multiple myeloma.
Pubmed
11
The proteasome inhibitor bortezomib is approved by the US Food and Drug Administration for treatment of mantle cell lymphoma.
Pubmed
12
Application of the proteasome inhibitor MG132 restored the ability of the Xcv ΔxopJ to attenuate the development of leaf necrosis.
Pubmed
13
We first generated a yeast strain with an epitope tagged proteasome subunit to which a proteasome inhibitor could be applied.
Pubmed
14
The impact of in vitro exposure to the proteasome inhibitor bortezomib was next evaluated in primary mantle cell lymphoma cells.
Pubmed
15
These studies explain a fundamental mechanism by which cells adapt to proteotoxic stress and suggest strategies to mitigate proteasome inhibitor resistance.
Pubmed
16
We found that the reduction in tyrosinase levels that was induced by terrein was clearly recovered by MG-132, a proteasome inhibitor.
Pubmed
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Translations for proteasome inhibitor
Proteasome inhibitor ao longo do tempo
Proteasome inhibitor nas variantes da língua
Estados Unidos da América
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